My thoughts too.

It prompts an immune response that prevents cocaine reaching the brain, which in itself might be a good last-line of defence for someone relapsing, to prevent them from retriggering a cycle of dependency.

But what happens when a person suffering major withdrawals doesnt get a response from one line of coke? More lines of coke is what I would expect. What effects are extreme doses of cocaine going to have on other parts of the body when the user is upping their dose trying to get something to pass through the blood-brain barrier?