• TheAmishMan@lemmy.world
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    1 year ago

    I graduated pharmacy school 8 years ago. This was a thing that was taught in school. This is why you should talk to your pharmacist. Guaifenisin is another ‘garbage drug’ that does virtually nothing; just drink more water

    • kmkz_ninja@lemmy.world
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      1 year ago

      Guaifenisin seems to clear my chest congestion up pretty quickly. If I’m placeboing myself, then lalalala I’m not listening.

    • dantheclamman@lemmy.worldOP
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      1 year ago

      omg are you serious? I always felt like sudafed PE didn’t do much but I thought mucinex helped a bunch with sinus congestion. now I’m here not sure if anything is real.

      Edit for those interested: “extended-release guaifenesin was found to have no effect on all 3 patient-related outcome markers analyzed as measured by the Daily Cough and Phlegm Diary, Spontaneous Symptom Severity Assessment score, and the Wisconsin Upper Respiratory Symptom Survey.”

      Edit again with more: “The greatest effects of treatment with guaifenesin/pseudoephedrine were observed for nasal congestion and sinus headache. Time to overall relief was shorter with guaifenesin/pseudoephedrine (P = 0.038). Significantly more patients reported “the medication was helping during the day” on Day 2 with guaifenesin/pseudoephedrine (P = 0.002). Patient assessments of symptom relief showed a significant preference for guaifenesin/pseudoephedrine versus placebo”

    • PetDinosaurs@lemmy.world
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      1 year ago

      I’m with the others. Guaifenisin seems to work pretty well. Even on it’s own. And I’m a major skeptic.

      Not as well as pseudoephedrine or ibuprofen or acetaminophen, but it’s definitely better than dextromethorphan.

      I can’t even pretend to believe that last one does anything. Well, I think idiots use it to get high in a scary way.

    • Blaidd@lemm.ee
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      1 year ago

      Guaifenisin is definitely not a garbage drug, it’s very effective for me in ways that prove it works.

      • Ben Hur Horse Race@lemm.ee
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        1 year ago

        what does it do? I honestly dont know, I havent looked it up.

        just to say, you taking it and believing it has an effect is not proof. large, well regulated, double blind studies are proof.

        if you take it and it does something for you thats good and all you need to know, but it aint proof.

        thats reaaaal similar to people who took Ivermectin when they had covid who recovered from covid and say “thats proof Ivermectin cures covid”

        • Blaidd@lemm.ee
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          1 year ago

          It thins out mucus. The fact that it works very well for me is absolutely proof that it works. I started taking it on recommendation from my doctor. Please explain to me how this is at all analagous to people taking horse ivermectin after doctors denied giving them a prescription?

          Edit to add: guaifenisin is the main ingredient in Mucinex, to those who aren’t familiar

          • servermonky@lemmy.today
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            1 year ago

            I take guaifenisn to combat dry sinuses, and it’s helpful there for me. But I’m not sure I’ve seen a difference in on-label use.

            Unfortunately I deal with frequent nosebleeds and sinus headaches from dryness, and there aren’t a lot of options that work well for me

          • Ben Hur Horse Race@lemm.ee
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            1 year ago

            lots of doctors gave, and are still giving out ivermeticin on prescription. just the ones who ignore the clinical evidence.

            look I’m not saying it doesnt seem to work for you. I’m saying one person taking any med and seeing results is not “proof”, other than for yourself, but thats really all you need to worry about so it doesnt matter.

            • Blaidd@lemm.ee
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              1 year ago

              Guaifenisin aka Mucinex is an FDA approved drug. Maybe you should look it up since you clearly don’t know anything about it? Or just take the word of a stranger on the Internet who says they went to pharmacy school eight years ago

              • Ben Hur Horse Race@lemm.ee
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                1 year ago

                hey, I wasnt taking anyone’s word for anything. I was only saying one person’s experience isn’t proof, and I stand by that.

                I do owe you an apology though, it was late at night and I misunderstood- I confused guaifenisin with phenylephrine, so we were talking about different things which was totally my fault