Our News Team @ 11 with host Snot Flickerman

  • 19 Posts
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Joined 11 months ago
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Cake day: October 24th, 2023

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  • So the CBD thing really bugs me, in particular.

    One of my medications has one of those warnings about how you can’t have grapefruit while taking this medication. That’s because grapefruit is metabolized on a certain enzyme pathway that gets interrupted. That enzyme pathway is CYP3A4.

    You know what else takes that enzyme pathway? Fucking CBD. It also blocks the enzyme pathway, making any drugs administered less effective because they can’t bind to where they need to because the CBD molecule is already there, taking up space.

    So like, for me, these are life saving medications so fucking around with this is really stupid but literally no doctor told me this. I accidentally figured this out while doing research on CBD. It seems like its becoming more publicized now, but the bottom line is this:

    If you have medication that warns you that you should not eat grapefruit with this medication (about 60% of medications, I believe), that medication needs the same warning about CBD.

    https://www.pharmacytimes.com/view/cannabidiol-presents-conundrums

    Upon further evaluation, it was shown that CYP3A4 and CYP2C19 are the 2 major enzymes responsible for the metabolism of CBD; they are also responsible for the metabolism of many different drugs.







  • Walz as the Democratic vice-presidential candidate in an age when so many men have been “red-pilled” into reactionary politics — and with Vance as the other ticket’s comparison — is a real opportunity for a different vision of masculinity to culturally take root.

    In many ways, an excellent article, but I do take minor issue with the way it is framed here.

    I think that this different version of masculinity was always there, culturally. I think it was because if it wasn’t men like Walz would not exist already. Many men like this do and many men like this did. I think it does them a bit of a disservice to talk about their masculinity as though it’s not culturally accepted. Rather, it’s like the article discusses, the left just fails to meaningfully describe these men and why their masculinity is good and what you should aim for. Meanwhile Walz is seemingly actually fairly good at, if not necessarily articulating why his version of masculinity is good, showing why is it good.

    Which is also I think an aspect of why we forget that these men were always there culturally. Traditionally, these men have often been quiet stewards, not the kind of men who would seek any kind of media attention. So while the manosphere festered with freaks who simply won’t shut the fuck up with outright drivel, misogyny, and racism, these men have simply been… existing, being good fathers, uncles, and brothers in their families, not trying to win awards or accolades.



  • Here’s hoping they stick this time. I’m so sorry to hear, long ago one of my now ex-girlfriends was dealing with it. She would have to go to the hospital and get GI cocktails and I would stay awake with her and try to help her not panic because the GI cocktail numbed everything in your throat and she wouldn’t be able to feel herself breathing. As someone who has lots of panic about breathing issues, I totally understood why it would be panic inducing to not be able to feel yourself breathe, and this seemed like the only thing anyone was able to do for her when it got really bad. Just a shitty choice, take the GI cocktail and get relief but also panic, or don’t take it and feel like you’re choking on your own vomit. So , fuck it just sucks so much. I really hope for the best for you.